Description: Leucocyte Trafficking : The Role of Fucosyltransferases and Selectins, Paperback by Hamann, A. (EDT); Asadullah, Khusru (EDT); Schottelius, A. (EDT), ISBN 3662053993, ISBN-13 9783662053997, Like New Used, Free P&P in the UK An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.
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Book Title: Leucocyte Trafficking : The Role of Fucosyltransferases and Selec
Number of Pages: 242 Pages
Publication Name: Leucocyte Trafficking: the Role of Fucosyltransferases and Selectins
Language: English
Publisher: Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
Item Height: 210 mm
Subject: Medicine, Biology, Psychiatry
Publication Year: 2013
Type: Textbook
Item Weight: 339 g
Author: Khusru Asadullah, A. Hamann, A. Schottelius
Item Width: 148 mm
Series: Ernst Schering Foundation Symposium Proceedings
Format: Paperback
